- Population: 18,132 (Change since 1990: +8.9%)
- Created: November 16, 1820
- County seat: Perryville
- Largest town: Perryville (Pop. 7,667)
- Name origin: Oliver Perry
- Allens Landing (Historical)
- Located on the Mississippi River at the end of CR 220 northeast of Perryville.
Route E is known as Allens Landing Road.
- Latitude & Longitude: 37°49'42" N, 89°43'42" W
- Survey: T. 36 N., R. 12 E., Sec. 17
- Elevation: 380
- Civil township: Bois Brule
- USGS Quad: Rockwood (Not shown)
- Altenburg (Fourth-class city)
- Population: 309 (Change since 1990: +0.7%)
- Located at the intersections of Route A, Route C, and Route Y
just east of Frohna
- Latitude & Longitude: 37°37'53" N, 89°34'53" W
- Name origin: Altenburg, Germany
- Founded: 1839
- Apple Creek (Unincorporated)
- Previously known as: Schnurbusch
- Located on Route F west of Uniontown
- Latitude & Longitude: 37°36'46" N, 89°45'03" W
- Survey: T. 34 N., R. 12 E., Sec. 31
- Civil township: Union
- School district: Perry County 32
- USGS Quad: Friedheim
- Barks (Historical)
- Located on Route T west of Silver Lake
- Latitude & Longitude: 37°40'35" N, 90°03'60" W
- Survey: T. 34 N., R. 9 E., Sec. 5
- Elevation: 870
- Civil township: St. Marys
- USGS Quad: Parker Lake (Not shown)
- Maps: 1904 McNally, 1920 Clason, and MoDOT
- Belgique (Unincorporated)
- Formerly incorporated with a 1970 population of 18
- Located on Route C east of McBride
- Latitude & Longitude: 37°50'15" N, 89°46'52" W
- Elevation: 372
- Civil township: Bois Brule
- School district: Perry County 32
- USGS Quad: Belgique
- Biehle (Unincorporated)
- Population: 11 (Change since 1990: +22.2%)
- Located on Route B just north of Cape County border
- Latitude & Longitude: 37°36'19" N, 89°50'24" W
- Civil township: Cinque Hommes
- School district: Perry County 32
- USGS Quad: Friedheim
- Birmingham (Historical)
- Founded in the early 1800s after iron was discovered.
- Previously known as: Gerler
- Located just north of Apple Creek near the Mississippi River.
- Latitude & Longitude: 37°34'04" N, 89°31'44" W
- Elevation: 370
- Civil township: Brazeau
- USGS Quad: Neelys Landing (Not shown)
- Maps: 1841 (Road shown connecting Birmingham with Perryville), 1857 Colton (Birmingham shown incorrectly on south side of Apple Creek), 1881 Chester RR (Shows Birmingham 8 miles south of Wittenberg), and 1920 Clason (Gerler)
- Sources: Houck (vol. 1 and p. 161)
- Bishop Landing (Historical)
- Located along the Mississippi River near Point Rest
- Latitude & Longitude: 37°49'07" N, 89°42'47" W
- Survey: T. 36 N., R. 12 E., Sec. 16
- Elevation: 350
- Civil township: Bois Brule
- USGS Quad: Rockwood (Not shown)
- Bois Brule (Historical)
- Brazeau (Unincorporated)
- Located at the eastern intersection of Route C and Route D
- Latitude & Longitude: 37°39'40" N, 89°39'10" W
- Civil township: Union
- School district: Perry County 32
- USGS Quad: Crosstown
- Probably named for Joseph Brazeau,
a St. Louis merchant from 1791 to 1779, or a member of his family
- Source: Ramsay (p. 47)
- Brewer (Unincorporated)
- Previously known as: Brewerville
- Located at the intersection of US 61 and Route M east of I-55
- Latitude & Longitude: 37°46'51" N, 89°55'31" W
- Elevation: 570
- Civil township: Saline
- School district: Perry County 32
- USGS Quad: Lithium
- Named for the Brewer family which established a homestead here.
- Map: 1889 (Brewerville)
- Claryville (Unincorporated)
- Formerly incorporated with a 1960 population of 30
- Alternate name: West Chester
- Located opposite the Mississippi River from Chester, IL
- Latitude & Longitude: 37°53'32" N, 89°49'44" W
- Civil township: Bois Brule
- School district: Perry County 32
- USGS Quad: Chester (Shown as incorporated)
- Founded: 1873 by Capt. C. C. Williams
- Corners (Historical)
- A post office in 1907
- Located on Route BB near Whitewater River and the St. Francois County line
- Latitude & Longitude: 37°39'23" N, 90°06'39" W
- Survey: T. 34 N., R. 8 E., Sec. 14
- Elevation: 806
- Civil township: St. Marys
- USGS Quad: Parker Lake (Not shown)
- Map: MoDOT
- Crosstown (Unincorporated)
- Formerly incorporated with a 1970 population of 66
- Located at intersection Route C and Route P
- Latitude & Longitude: 37°44'47" N, 89°43'40" W
- Elevation: 570
- Civil township: Salem
- School district: Perry County 32
- USGS Quad: Crosstown
- Dresden (Historical)
- Located just east of Altenburg
- Civil township: Brazeau
- Named for Dresden, Germany, one of the cities from which
the Lutheran immigrants came
- Founded: ca. 1839
- Maps: 1855 (Dresden shown as only town in eastern Perry County), 1857 Colton (Shows Dresden along with Altenburg, Wittenberg, Seelitz, and and Frohna)
- Eureka (Historical)
- Located at the intersection of Route D and Route U east of Longtown
- Latitude & Longitude: 37°40'44" N, 89°44'13" W
- Survey: T. 34 N., R. 12 E., Sec. 5
- Elevation: 642
- Civil township: Union
- USGS Quad: Crosstown (Shows Eureka School)
- Map: MoDOT
- Farrar (Unincorporated)
- Located along CR 328 just off Route C northwest of Brazeau
- Latitude & Longitude: 37°42'08" N, 89°41'19" W
- Survey: T. 35 N., R. 12 E., Sec. 27
- Civil township: Salem
- School district: Perry County 32
- USGS Quad: Crosstown
- Friedenberg (Unincorporated)
- Located on CR 302 southeast of Perryville
- Latitude & Longitude: 37°42'03" N, 89°47'38" W
- Survey: T. 35 N., R. 11 E., Sec. 35
- Elevation: 530
- Civil township: Central
- School district: Perry County 32
- USGS Quad: Perryville East
- Map: MoDOT
- Friendly Valley (Historical)
- Located southwest of Perryville on MO 51
- Latitude & Longitude: 37°41'24" N, 89°54'38" W
- Survey: T. 35 N., R. 10 E., Sec. 34
- Elevation: 600
- Civil township: Central
- USGS Quad: Perryville West
- Frohna (Fourth-class city)
- Population: 192 (Change since 1990: +18.5%)
- Located at the intersection of Route A and Route C just west of Altenburg
- Latitude & Longitude: 37°38'26" N, 89°37'09" W
- Name origin: Nieder-Frohna province, Germany
- Founded: 1839
- Post office: May 4, 1870 - Now
- Giboney (Unincorporated)
- Located on Route NN west of US 61
- Latitude & Longitude: 37°48'17" N, 89°59'26" W
- Civil township: Saline
- School district: Perry County 32
- USGS Quad: Lithium
- Station on the Saline Valley Line
- Possibly named for Mary H. Giboney, wife of railroad builder Louis Houck
- Grand Eddy (Historical)
- Alternate name: Baileys Landing
- Located near the mouth of Cinque Hommes Creek
- Latitude & Longitude: 37°45'18" N, 89°41'10" W
- Elevation: 400
- Civil township: Salem
- USGS Quad: Rockwood (Not shown)
- Station on the St. Louis and Memphis Line
- Maps: 1880, 1889, and 1920 Clason
- Highland (Unincorporated)
- Located on Route K between Perryville and Millheim
- Latitude & Longitude: 37°39'52" N, 89°53'29" W
- Elevation: 676
- Civil township: Cinque Hommes
- School district: Perry County 32
- USGS Quad: Perryville West
- Holschen Landing (Historical)
- Ingrams Mill (Historical)
- Located on the north bank of Apple Creek northeast of New Wells,
probably near Route C
- Survey: On or near Land Grant #1845
- Map: 1870 Brooks
- Laurel Hill (Historical)
- Laurel Hill had a post office from 1860 to 1871.
- Located southeast of Seventysix on the Mississippi River
- Probably named after "The Laurel", the ship owned
by John Wilkinson that sank here. Wilkinson later
founded Seventysix just upstream from this point.
- Maps: 1862, 1872, 1873, and 1877
- Leimbach Landing (Historical)
- Alternate name: Loimbach Landing
- Located along the Mississippi between Starland and Cape Cinque Hommes
- Latitude & Longitude: 37°42'01" N, 89°33'02" W
- Survey: T. 35 N., R. 13 E., Sec. 36
- Civil township: Brazeau
- USGS Quad: Altenburg
- Lithium (Village)
- Population: zero (Change since 1990: -100.0%)
- Located along Route M south of Route H
- Latitude & Longitude: 37°49'56" N, 89°53'02" W
- Name origin: Lithium carbonate
- Founded: 1882 by Charles F. Lawrence
- Longtown (Village)
- Population: 76 (Change since 1990: -29.0%)
- Located on US 61 between Uniontown and Perryville
- Latitude & Longitude: 37°40'12" N, 89°46'25" W
- Name origin: John Long
- Founded: 1819
- McBride (Unincorporated)
- Located on MO 51 between Perryville and the Mississippi River bridge
- Latitude & Longitude: 37°49'58" N, 89°50'24" W
- Civil township: Bois Brule
- School district: Perry County 32
- USGS Quad: Belgique
- Menfro (Unincorporated)
- Formerly incorporated with a 1960 population of 37
- Located on Route C at the railroad crossing north of Crosstown
- Latitude & Longitude: 37°46'37" N, 89°43'24" W
- Elevation: 371
- Civil township: Bois Brule
- School district: Perry County 32
- USGS Quad: Rockwood
- Station on the St. Louis and Memphis Line
- Post office: 1904 - Aug. 31, 1996
- Millheim (Unincorporated)
- Located at the intersection of Route O and Route K north of Sedgewickville
- Latitude & Longitude: 37°37'03" N, 89°53'14" W
- Survey: T. 34 N., R. 10 E., Sec. 25
- Elevation: 581
- Civil township: Cinque Hommes
- School district: Perry County 32
- USGS Quad: Sedgewickville
- Maps: 1889 Polk (Muhlheim) and 1904 McNally
- Parker Lake (Unincorporated)
- Located near Route T west of Silver Lake
- Latitude & Longitude: 37°41'12" N, 90°04'39" W
- Civil township: St. Marys
- School district: Perry County 32
- USGS Quad: Parker Lake
- Perryville (Fourth-class city)
- Population: 7,667 (Change since 1990: +10.6%)
- Located near intersections of I-55, US 61, and MO 51
- Latitude & Longitude: 37°43'34" N, 89°52'18" W
- Name origin: Oliver Perry
- Founded: Aug. 7, 1821
- Perryville Junction (Historical)
- Previously known as: St. Marys Junction
- Located just off Route H northwest of Lithium
- Latitude & Longitude: 37°51'51" N, 89°54'41" W
- Survey: T. 37 N., R. 10 E., Sec. 34
- Elevation: 375
- Civil township: Saline
- USGS Quad: Lithium (Not shown)
- Junction of Cape Girardeau Northern Line and Frisco mainline
- Pit (Historical)
- Pleasant Valley (Historical)
- Point Rest (Unincorporated)
- Alternate name: Bishop Landing
- Located near the levee east of intersection of Route C and Route E
- Latitude & Longitude: 37°48'58" N, 89°42'45" W
- Civil township: Bois Brule
- School district: Perry County 32
- USGS Quad: Rockwood
- Maps: 1920 Clason and MoDOT
- Port Perry (Historical)
- Prattes Landing (Historical)
- Red Rock (Historical)
- Located on the Mississippi River between Menfro and Seventysix
- Latitude & Longitude: 37°44'57" N, 89°40'13" W
- Survey: T. 35 N., R. 12 E., Sec. 11
- Elevation: 440
- Civil township: Salem
- USGS Quad: Crosstown (Not shown)
- Ridge (Historical)
- Located at the end of Route Y south of Starland
- Latitude & Longitude: 37°41'08" N, 89°35'19" W
- Survey: T. 34 N., R. 13 E., Sec. 3
- Civil township: Brazeau
- USGS Quad: Altenburg (Shows Ridge School)
- Map: 1904 McNally
- Rock Spring (Historical)
- Saline Junction (Unincorporated)
- Located at the end of Route V north of Perryville
- Latitude & Longitude: 37°47'20" N, 89°53'12" W
- Survey: T. 36 N., R. 10 E., Sec. 36
- Elevation: 531
- Civil township: Saline
- School district: Perry County 32
- USGS Quad: Lithium
- Schalls (Historical)
- Alternate name: Schall's
- Located at the intersection of Route D and CR 414 west of Brazeau
- Elevation: 578
- Civil township: Union
- Schumer Springs (Historical)
- Located on CR 634 near South Fork Apple Creek west of Biehle
- Latitude & Longitude: 37°36'10" N, 89°52'38" W
- Survey: T. 34 N., R. 10 E., Sec. 36
- Civil township: Cinque Hommes
- USGS Quad: Sedgewickville
- Map: MoDOT
- Seelitz (Historical)
- Sereno (Unincorporated)
- Located on MO 51 between McBride and Perryville
- Latitude & Longitude: 37°47'52" N, 89°51'04" W
- Elevation: 621
- Civil township: Bois Brule
- School district: Perry County 32
- USGS Quad: Belgique
- Seventysix (Historical)
- Alternate name: Seventy-Six
- Located just past the end of Route D on the Mississippi River
- Latitude & Longitude: 37°43'12" N, 89°36'44" W
- Survey: T. 35 N., R. 13 E., Sec. 20
- Civil township: Brazeau
- USGS Quad: Altenburg
- Founded: by John Wilkinson
- Maps: 1862 (Shows location as "Wilkinsons"), 1872 (Continues to show place as "Wilkinsons"), 1886 (Shows Seventy-Six), 1920 Clason (Seventy-Six), and MoDOT (Seventy Six)
- Shakertowne (Unincorporated)
- Located at the intersection Route B and Route K south of Perryville
- Survey: T. 35 N., R. 10 E., Sec. 36
- Map: MoDOT
- Silver Lake (Unincorporated)
- Located at intersection Route T and Route CC southwest of Perryville
- Latitude & Longitude: 37°41'01" N, 89°59'24" W
- Survey: T. 34 N., R. 9 E., Sec. 1
- Civil township: St. Marys
- School district: Perry County 32
- USGS Quad: Perryville West
- Stagetown (Historical)
- Starland (Unincorporated)
- Alternate name: Star Landing
- Located on CR 440 past the end of Route Y on the Mississippi River
- Latitude & Longitude: 37°42'33" N, 89°35'07" W
- Survey: T. 35 N., R. 13 E., Sec. 27
- Civil township: Brazeau
- School district: Altenburg 48
- USGS Quad: Altenburg
- Uniontown (Unincorporated)
- Previously known as: Paitzdorf
- Located at intersection US 61, Route F, and Route A north of Old Appleton
- Latitude & Longitude: 37°36'53" N, 89°42'50" W
- Elevation: 576
- Civil township: Union
- School district: Perry County 32
- USGS Quad: Oak Ridge
- Presumably named after the Union side during the Civil War.
- Weatherly (Historical)
- Located on the Mississippi River two miles southeast of Grand Eddy
- USGS Quad: Crosstown (Not shown)
- Short-lived passenger station on the Frisco St. Louis and Memphis Line between
Grand Eddy and Wilkinson
- Wilkinson (Historical)
- Alternate name: Wilkinson Landing
- Located on the Mississippi River opposite Wilkinson Island
two miles northwest of Seventysix
- USGS Quad: Crosstown (Not shown)
- Station on the Frisco St. Louis and Memphis Line between
Weatherly and Seventysix
- Wittenberg (Unincorporated)
- Alternate name: Wittenburg
- Located at the eastern end of Route A on the Mississippi River
- Latitude & Longitude: 37°39'09" N, 89°31'28" W
- Civil township: Brazeau
- School district: Altenburg 48
- USGS Quad: Altenburg
- Lutheran immigrants named the town after Wittenberg,
Germany, the city where Martin Luther started the Protestant Reformation.
- Founded: ca. 1839 by Rev. Maximilian Oertel
- Post office: 1862 - Aug. 31, 1996
- Maps: 1857 Colton (Shows Wittenberg along with the other nearby German towns), 1857 Johnson (Town incorrectly shown as "Winterburg"), 1872 (Town spelled "Wittenburg"), and 1904 McNally (Shown as a station on the Frisco railroad 11 miles north of Neelys Landing)
- Yount (Unincorporated)
- Previously known as: Younts Store
- Alternate name: Younts
- Located on Route J west of MO 51
- Latitude & Longitude: 37°36'19" N, 90°02'20" W
- Survey: T. 34 N., R. 9 E., Sec. 33
- Elevation: 632
- Civil township: St. Marys
- School district: Perry County 32
- USGS Quad: Patton
- Map: 1886 (Shown as Younts Store)
Name origin
Named for Oliver Perry, naval war hero from War of 1812
| Year | Population | Percent change |
|---|
| 1820 | 1,599 | -- |
| 1830 | 3,349 | +109.4% |
| 1840 | 5,760 | +72.0% |
| 1850 | 7,215 | +25.3% |
| 1860 | 9,128 | +26.5% |
| 1870 | 9,877 | +8.2% |
| 1880 | 11,895 | +20.4% |
| 1890 | 13,237 | +11.3% |
| 1900 | 15,134 | +14.3% |
| 1910 | 14,898 | -1.6% |
| 1920 | 14,434 | -3.1% |
| 1930 | 13,707 | -5.0% |
| 1940 | 15,358 | +12.0% |
| 1950 | 14,890 | -3.0% |
| 1960 | 14,642 | -1.7% |
| 1970 | 14,393 | -1.7% |
| 1980 | 16,784 | +16.6% |
| 1990 | 16,648 | -0.8% |
| 2000 | 18,132 | +8.9% |