- Location: Mississippi County, Missouri
- Legal status: Fourth-class city
- Population: 364 (Change since 1990: -3.2%)
- Founded: May 14, 1900 by K. N. Smith
- Name origin: William Wyatt
- Previously known as: Payne and Smithton
- Located adjacent to Wilson City just south
of US 60/62
- Latitude: 36°55'09" N (+36.9192)
- Longitude: 89°12'36" W (-89.2100)
- Civil township: Ohio
- Land area: 1.1 square miles
- Water area: 0.07 square miles (47.1 acres)
As the crow flies, Wyatt is...
Name origin
Named for William Wyatt, postmaster
Previous names
First named Payne for postmaster Jasper Payne.
Later called Smithton.
| Year | Population | Percent change |
|---|
| 1930 | 199 | -- |
| 1940 | 417 | +109.5% |
| 1950 | 345 | -17.3% |
| 1960 | 711 | +106.1% |
| 1970 | 562 | -21.0% |
| 1980 | 441 | -21.5% |
| 1990 | 376 | -14.7% |
| 2000 | 364 | -3.2% |