- Location: Mississippi County, Missouri
- Legal status: Fourth-class city
- Population: 3,227 (Change since 1990: -5.5%)
- Founded: February 2, 1883
- Previously known as: Hibbard
- Located at the intersection MO 80 and MO 105
- Latitude: 36°46'46" N (+36.7795)
- Longitude: 89°23'05" W (-89.3848)
- Elevation: 307 feet above sea level
- Civil township: St. James
- Land area: 1.3 square miles
As the crow flies, East Prairie is...
| Year | Population | Percent change |
|---|
| 1900 | 388 | -- |
| 1910 | 1,243 | +220.4% |
| 1920 | 1,124 | -9.6% |
| 1930 | 1,385 | +23.2% |
| 1940 | 2,469 | +78.3% |
| 1950 | 3,033 | +22.8% |
| 1960 | 3,449 | +13.7% |
| 1970 | 3,275 | -5.0% |
| 1980 | 3,713 | +13.4% |
| 1990 | 3,416 | -8.0% |
| 2000 | 3,227 | -5.5% |