- Population: 13,427 (Change since 1990: -7.0%)
- Created: February 14, 1845
- County seat: Charleston
- Largest town: Charleston (Pop. 4,732)
- Name origin: Mississippi River
- Airline Acres (Unincorporated)
- Located at the intersection MO 105 and MO 102 northeast of East Prairie
- Latitude & Longitude: 36°48'12" N, 89°21'29" W
- Survey: T. 25 N., R. 16 E., Sec. 19
- Elevation: 308
- Civil township: St. James
- School district: East Prairie R-2
- USGS Quad: Anniston (Shown as an incorporated place)
- Alfalfa Center (Unincorporated)
- Previously known as: Birds Mill
- Located at the intersection Route K and Route Y north of Wilson City
- Latitude & Longitude: 36°57'47" N, 89°12'26" W
- Survey: T. 27 N., R. 17 E., Sec. 27
- Elevation: 316
- Civil township: Ohio
- School district: Charleston R-1
- USGS Quad: Wyatt
- Station on the C.A.T. Line between Rodney and Birds Point
- Anniston (Fourth-class city)
- Population: 285 (Change since 1990: -1.0%)
- Located on MO 75 northeast of East Prairie
- Latitude & Longitude: 36°49'28" N, 89°19'35" W
- Founded: May 7, 1895
- Atchers (Historical)
- Baldwinsville (Historical)
- Beckwith (Historical)
- Alternate name: Bickwith
- Probably located on a county road north of Crosno near
the old channel of the river. In its day, Beckwith was a ferry
landing on the Mississippi but the river's course has changed since then.
- Named for Newman Beckwith, who settled here
from Virginia in 1812.
- Maps: 1838, 1857 Johnson, 1862 War Colton (Bickwiths), 1869, and 1872
- Belmont (Historical)
- Located at the eastern end of MO 80 on the Mississippi River
opposite Columbus, Kentucky
- Latitude & Longitude: 36°45'50" N, 89°07'40" W
- Survey: T. 25 N., R. 18 E., Sec. 32
- Elevation: 310
- Civil township: Mississippi
- USGS Quad: Wickliffe SW (Not shown)
- Terminus of the Belmont Branch railroad
- Maps: 1861, 1862, 1863 Mississippi R. (Belmont or Baldwinsville), 1865 (Belmont Landing), 1866 (Spelled Bellemont), 1867, 1869 (Shown as terminus of newly constructed Iron Mountain railroad), 1872 (Belmont Landing), 1880, 1895 McNally, 1904 McNally, 1944 (Railroad no longer extends all the way to Belmont), and MoDOT
- Bertrand (Fourth-class city)
- Population: 740 (Change since 1990: +6.9%)
- Located at the intersection of US 62 and Route B just north of I-57 Exit 4
- Latitude & Longitude: 36°54'37" N, 89°26'54" W
- Founded: October 24, 1859 by Henry and Melvina Deal
- Birds Point (Historical)
- Alternate name: Ohio City
- Located at intersection US 60/62 and Route K northeast of Wyatt and southwest of the
confluence of the Mississippi and Ohio Rivers.
- Latitude & Longitude: 36°57'57" N, 89°09'23" W
- Survey: T. 27 N., R. 18 E., Sec. 19
- Elevation: 316
- Civil township: Ohio
- USGS Quad: Wyatt
- Named for Abraham Bird who settled here in 1802.
- Birdsville (Historical)
- Alternate name: Greenfield
- Located along the Mississippi River west of Birds Point
- Latitude & Longitude: 36°57'54" N, 89°10'18" W
- Elevation: 319
- Civil township: Ohio
- USGS Quad: Wyatt (Not shown)
- Maps: 1861 (Birdville), 1862 (Birdville), 1872, 1872, 1874 (Greenfield), and 1877
- Buckeye (Historical)
- Located at the intersection US 62 and Route CC southwest of Bertrand
- Latitude & Longitude: 36°54'16" N, 89°29'33" W
- Survey: T. 26 N., R. 14 E., Sec. 13
- Elevation: 311
- Civil township: Long Prairie
- USGS Quad: Bertrand (Benchmark shown)
- Station on C.A.T. Line between Sikeston and Bertrand
- Maps: 1897 Galbraith, 1904 McNally, and 1944
- Catalpa (Historical)
- Located southeast of Charleston along CR 325 (old railroad alignment)
just northwest of the bridge over Spillway Ditch
- Latitude & Longitude: 36°52'58" N, 89°17'40" W
- Survey: T. 26 N., R. 16 E., Sec. 23
- Elevation: 313
- Civil township: Tywappity
- USGS Quad: Charleston (Not labeled, but does show small cluster of buildings)
- Station on the Belmont Branch between Hallett and Samos
- Charleston (Third-class city)
- Population: 4,732 (Change since 1990: -6.9%)
- Latitude & Longitude: 36°55'17" N, 89°20'47" W
- Founded: May 13, 1837 by Joseph Moore
- Coulter (Historical)
- Located along CR 321 (old Cotton Belt railroad)
northeast of the end of Route JJ and southwest of Wyatt
- Latitude & Longitude: 36°53'09" N, 89°15'09" W
- Survey: T. 26 N., R. 17 E., Sec. 19
- Elevation: 314
- Civil township: Ohio
- USGS Quad: Charleston (Benchmark shown)
- Station on the Cotton Belt Line between Samos and Wyatt
- Crenshaw (Historical)
- Located just southeast of Charleston, near where Route UU overpasses I-57
- Latitude & Longitude: 36°54'31" N, 89°20'03" W
- Survey: T. 26 N., R. 16 E., Sec. 9
- Elevation: 321
- Civil township: Tywappity
- USGS Quad: Charleston (Not shown)
- Point on the Belmont Branch between Charleston and Hallett
- Crosno (Unincorporated)
- Located at the end of Route F along the old channel of the Mississippi
- Latitude & Longitude: 36°47'51" N, 89°10'38" W
- Survey: T. 25 N., R. 17 E., Sec. 23
- Elevation: 312
- Civil township: Mississippi
- School district: East Prairie R-2
- USGS Quad: Wickliffe SW
- Station on the Belmont Branch between Deventer and Belmont
- Defield (Historical)
- Located at the intersection Route BB and the old railroad alignment southwest of East Prairie
- Latitude & Longitude: 36°45'37" N, 89°24'35" W
- Survey: T. 24 N., R. 15 E., Sec. 2
- Elevation: 301
- Civil township: St. James
- USGS Quad: East Prairie (Not shown)
- Point on the Cotton Belt Line between Henderson Mound and East Prairie
- Dermons Mills (Historical)
- Deventer (Unincorporated)
- Located at the intersection MO 77 and the old Belmont Branch railroad alignment
south of Wyatt
- Latitude & Longitude: 36°49'20" N, 89°12'42" W
- Survey: T. 25 N., R. 17 E., Sec. 9-10
- Civil township: Mississippi
- School district: Charleston R-1
- USGS Quad: Wickliffe SW
- Point on the Belmont Branch railroad between Henson and Crosno
- Map: 1944
- Dirk (Historical)
- Dogwood (Unincorporated)
- Previously known as: Sands
- Latitude & Longitude: 36°49'31" N, 89°27'13" W
- Survey: T. 25 N., R. 15 E., Sec. 8
- Civil township: Long Prairie
- School district: East Prairie R-2
- USGS Quad: East Prairie
- Dorena (Unincorporated)
- Located at the intersection MO 102 and MO 77
- Latitude & Longitude: 36°36'58" N, 89°14'14" W
- Survey: T. 23 N., R. 17 E., Sec. 20
- Civil township: James Bayou
- School district: East Prairie R-2
- USGS Quad: Hickman
- Maps: 1912 and 1944
- East Prairie (Fourth-class city)
- Population: 3,227 (Change since 1990: -5.5%)
- Located at the intersection MO 80 and MO 105
- Latitude & Longitude: 36°46'46" N, 89°23'05" W
- Founded: February 2, 1883
- Fish Lake (Historical)
- Fuget (Historical)
- Alternate name: Fugett
- Located along CR 319 northwest of Crosno
- Latitude & Longitude: 36°48'32" N, 89°11'31" W
- Survey: T. 25 N., R. 17 E., Sec. 14
- Elevation: 306
- Civil township: Mississippi
- USGS Quad: Wickliffe SW (Not shown)
- Point on the Belmont Branch between Deventer and Crosno
- Hallett (Historical)
- Located southeast of Charleston near the intersection of Route UU and CR 325
- Latitude & Longitude: 36°54'01" N, 89°19'20" W
- Survey: T. 26 N., R. 16 E., Sec. 16
- Elevation: 321
- Civil township: Tywappity
- USGS Quad: Charleston (Not shown)
- Station on the Belmont Branch between Charleston and Catalpa
- Harrison (Historical)
- Henson (Unincorporated)
- Alternate name: Henson Station
- Located on a county road just north of Route D
- Latitude & Longitude: 36°51'22" N, 89°15'09" W
- Survey: T. 26 N., R. 17 E., Sec. 31
- Civil township: Mississippi
- School district: Charleston R-1
- USGS Quad: Anniston
- Station on the Belmont Branch eight miles southeast of Charleston
- Maps: 1865, 1895 McNally, and 1918
- Source: Wilson's Directory
- Hopewell (Historical)
- Hough (Historical)
- Alternate name: Hough's Station
- Located northeast of Charleston along the old railroad alignment, probably near Route J
- Latitude & Longitude: 36°56'44" N, 89°16'01" W
- Survey: T. 27 N., R. 16 E., Sec. 36
- Elevation: 317
- Civil township: Tywappity
- USGS Quad: Charleston (Not shown)
- Station on the C.A.T. Line located between Charleston and Birds Point
- Maps: 1877, 1880, and 1889
- Source: Wilson's Directory
- Howletts (Historical)
- Located just southwest of Samos
- Latitude & Longitude: 36°51'34" N, 89°17'08" W
- Survey: T. 26 N., R. 16 E., Sec. 35
- Elevation: 311
- Civil township: Tywappity
- USGS Quad: Anniston (Not shown)
- Point on the Cotton Belt Line between Anniston and Samos
- James Bayou (Historical)
- Alternate name: St. James
- Located along the Mississippi River southeast of Bayouville, near the end
of Route WW
- Survey: T. 23 N., R. 16 E., Sec. 17
- USGS Quad: Bayouville (Not shown)
- Maps: 1861 (St. James), 1862 (St. James), 1865 (St. James), 1869 (St. James), 1872 (James Bayou), and 1886 (James Bayou)
- Luby (Historical)
- Located northeast of Wyatt, probably along US 60
- Civil township: Ohio
- USGS Quad: Wyatt (Not shown)
- Flagstop on the Cotton Belt Line between Wyatt and Birds Point
- Lucas Landing (Historical)
- Located on the old channel of the Mississippi north of Crosno
- Latitude & Longitude: 36°48'31" N, 89°10'44" W
- Survey: T. 25 N., R. 17 E., Sec. 14
- Elevation: 300
- Civil township: Mississippi
- USGS Quad: Wickliffe SW (Not shown)
- McFadden Landing (Historical)
- Located along the Mississippi River north of Belmont
opposite the southern tip of Islands Nos. 2, 3 and 4
- Latitude & Longitude: 36°47'13" N, 89°07'48" W
- Survey: T. 25 N., R. 18 E., Sec. 29
- Elevation: 300
- Civil township: Mississippi
- USGS Quad: Wickliffe SW (Not shown)
- Medley (Historical)
- Alternate name: Medley Landing
- Located along CR 507 on the old channel of the Mississippi
south of Wolf Island No. 5 and north of Medley Bar
- Latitude & Longitude: 36°40'27" N, 89°10'24" W
- Survey: T. 23 N., R. 17 E., Sec. 1
- Civil township: Wolf Island
- USGS Quad: Wolf Island (Not shown)
- Named for John C. Medley
- Miller Landing (Historical)
- Located along the old channel of the Missisippi opposite Islands
Nos. 2, 3, and 4 south of O'Bryan Landing
- Latitude & Longitude: 36°49'60" N, 89°10'46" W
- Survey: T. 25 N., R. 17 E., Sec. 11
- Elevation: 295
- Civil township: Mississippi
- USGS Quad: Wickliffe SW (Not shown)
- Never Spur (Historical)
- Located at the intersection US 62 and the old railroad
alignment just east of Bertrand
- Latitude & Longitude: 36°54'47" N, 89°26'02" W
- Survey: T. 26 N., R. 15 E., Sec. 9
- Elevation: 322
- Civil township: Long Prairie
- USGS Quad: Bertrand (Benchmark shown)
- Point on the C.A.T. Line between Bertrand and Charleston
- Norfolk (Historical)
- Located along the Mississippi River on CR 303 beyond the end of Route HH
- Latitude & Longitude: 36°55'46" N, 89°07'02" W
- Survey: T. 26 N., R. 18 E., Sec. 4
- Elevation: 313
- Civil township: Ohio
- USGS Quad: Wickliffe (Not shown)
- Maps: 1847, 1857 Colton, 1862, 1866, and 1880
- Oak Grove (Historical)
- O'Bryan Landing (Historical)
- Located northeast of Deventer along the old channel of the Mississippi
near O'Bryan Towhead and Islands Nos. 2, 3, and 4
- Latitude & Longitude: 36°50'34" N, 89°10'31" W
- Survey: T. 25 N., R. 17 E., Sec. 1
- Elevation: 305
- Civil township: Mississippi
- USGS Quad: Wickliffe SW (Not shown)
- Pinhook (Village)
- Population: 48 (Change since 1990: -7.7%)
- Located on Route VV west of Route FF
- Latitude & Longitude: 36°44'21" N, 89°16'04" W
- Pritchard Landing (Historical)
- Located near the end of Route HH south of Norfolk
- Latitude & Longitude: 36°55'03" N, 89°07'13" W
- Survey: T. 26 N., R. 18 E., Sec. 9
- Elevation: 295
- Civil township: Ohio
- USGS Quad: Wickliffe (Not shown)
- Pulltight (Historical)
- Located south of Anniston on MO 75 just north of MO 80
- Latitude & Longitude: 36°46'57" N, 89°19'09" W
- Survey: T. 25 N., R. 16 E., Sec. 28
- Elevation: 306
- Civil township: St. James
- USGS Quad: Anniston (Shows Pulltight Church)
- Rodney (Historical)
- Located on CR 207 northwest of Wilson City
- Latitude & Longitude: 36°57'26" N, 89°14'05" W
- Survey: T. 27 N., R. 17 E., Sec. 29
- Elevation: 317
- Civil township: Ohio
- USGS Quad: Wyatt (Benchmark shown)
- Station on C.A.T. Line between Hough and Alfalfa Center
- Maps: 1886 and 1902
- Rumsey Spur (Historical)
- Located east of Hough
- Latitude & Longitude: 36°57'00" N, 89°15'22" W
- Survey: T. 27 N., R. 17 E., Sec. 31
- Elevation: 315
- Civil township: Tywappity
- USGS Quad: Charleston (Not shown)
- Point on the C.A.T. Line between Hough and Rodney
- Rush Ridge (Historical)
- Alternate name: Rush's Ridge
- Located at intersection CR 305 and CR 307 (?) northeast of Wyatt
- Latitude & Longitude: 36°55'44" N, 89°10'45" W
- Elevation: 318
- Civil township: Ohio
- USGS Quad: Wyatt (Shows Rush Ridge Cemetery)
- Named after William Rush, who settled here in 1813.
- Maps: 1862, 1866, 1867, and 1880
- Samos (Unincorporated)
- Previously known as: Belmont Junction
- Located at the intersection CR 325 and CR 321 beyond the end of Route JJ
- Latitude & Longitude: 36°52'05" N, 89°16'35" W
- Survey: T. 26 N., R. 16 E., Sec. 25
- Elevation: 314
- Civil township: Tywappity
- School district: Charleston R-1
- USGS Quad: Anniston
- Junction of the Belmont Branch and the Cotton Belt railroads, which intersected at right angles here
- Sands (Historical)
- Smithton (Historical)
- Texas Bend (Historical)
- Located at intersection Route N and Route O north of Charleston
- Latitude & Longitude: 36°58'48" N, 89°21'23" W
- Survey: T. 27 N., R. 16 E., Sec. 17
- Elevation: 322
- Civil township: Tywappity
- USGS Quad: Charleston (Shows Texas Bend Cemetery)
- Thirty Four Corner (Unincorporated)
- Alternate name: Thirtyfour Corner
- Located at the intersection of MO 77 and MO 80
- Latitude & Longitude: 36°46'36" N, 89°12'39" W
- Survey: T. 25 N., R. 17 E., Sec. 34
- Elevation: 304
- Civil township: Mississippi
- School district: East Prairie R-2
- USGS Quad: Wickliffe SW (Labeled as "34 Corner")
- Probably named for its location at the northwest corner of Section 34
- Thompson Landing (Historical)
- Located on the Mississippi River northeast of Charleston
along CR 203, about 19.7 river miles above the confluence of the Ohio
- Latitude & Longitude: 37°01'60" N, 89°16'12" W
- Elevation: 325
- Civil township: Tywappity
- USGS Quad: Cache (Not shown)
- Map: 1976 Mississippi River
- Three States (Historical)
- Company town of the Three States Lumber Company. Formerly
incorporated.
- Alternate name: Three States Landing
- Located somewhere southwest of Wolf Island
- Latitude & Longitude: 36°37'04" N, 89°16'33" W
- Survey: T. 23 N., R. 16 E., Sec. 24
- Elevation: 299
- Civil township: James Bayou
- USGS Quad: Bondurant
- Maps: 1897 Galbraith and 1897 McNally
- Source: Powell (p. 155)
- Vater (Historical)
- Alternate name: Vater
- Located just southwest of Anniston
- Latitude & Longitude: 36°49'07" N, 89°20'10" W
- Survey: T. 25 N., R. 16 E., Sec. 16
- Elevation: 311
- Civil township: St. James
- USGS Quad: Anniston (Not shown)
- Point on the Cotton Belt Line between East Prairie and Anniston
- Whiting (Unincorporated)
- Formerly incorporated
- Located on MO 105 just northeast of East Prairie
- Latitude & Longitude: 36°47'20" N, 89°22'26" W
- Civil township: St. James
- School district: East Prairie R-2
- USGS Quad: Anniston (Shown as an incorporated place)
- Wilson City (Village)
- Population: 165 (Change since 1990: -21.4%)
- Located at intersection US 60/62 and MO 77
- Latitude & Longitude: 36°55'21" N, 89°13'26" W
- Name origin: Rev. Charles Wilson
- Wolf Island (Unincorporated)
- Located at the intersection MO 77 and Route A.
Old maps show the town and post office at varying locations but
always near Wolf Island itself (Island No. 5).
- Latitude & Longitude: 36°44'21" N, 89°12'37" W
- Civil township: Wolf Island
- School district: East Prairie R-2
- USGS Quad: Wolf Island
- Maps: 1838 (Part of Scott County), 1857 Colton, 1861, 1865, 1867, 1869, 1872, 1880 (Shown in two different places), 1889 Polk, 1895 McNally, 1904 McNally, 1918, and 1944
- Woodsdale (Historical)
- Located southwest of Wyatt
- Civil township: Ohio
- USGS Quad: Wyatt (Not shown)
- Flagstop on the Cotton Belt Line between Coulter and Wyatt
- Wyatt (Fourth-class city)
- Population: 364 (Change since 1990: -3.2%)
- Located adjacent to Wilson City just south
of US 60/62
- Latitude & Longitude: 36°55'09" N, 89°12'36" W
- Name origin: William Wyatt
- Founded: May 14, 1900 by K. N. Smith
Name origin
Named after the Mississippi River.
| Year | Population | Percent change |
|---|
| 1850 | 3,123 | -- |
| 1860 | 4,859 | +55.6% |
| 1870 | 4,982 | +2.5% |
| 1880 | 9,270 | +86.1% |
| 1890 | 10,134 | +9.3% |
| 1900 | 11,837 | +16.8% |
| 1910 | 14,557 | +23.0% |
| 1920 | 12,860 | -11.7% |
| 1930 | 15,762 | +22.6% |
| 1940 | 23,149 | +46.9% |
| 1950 | 22,551 | -2.6% |
| 1960 | 20,695 | -8.2% |
| 1970 | 16,647 | -19.6% |
| 1980 | 15,726 | -5.5% |
| 1990 | 14,442 | -8.2% |
| 2000 | 13,427 | -7.0% |