- Population: 198,099 (Change since 1990: +15.6%)
- Created: December 8, 1818
- County seat: Hillsboro
- Largest town: Arnold (Pop. 19,965)
- Name origin: Thomas Jefferson
- Antonia (Unincorporated)
- Previously known as: San Antonia
- Located on Route M west of Barnhart
- Latitude & Longitude: 38°21'45" N, 90°27'56" W
- Survey: T. 42 N., R. 5 E., Sec. 21
- Civil township: Imperial
- School district: Fox C-6
- USGS Quad: Herculaneum
- Arnold (Third-class city)
- Population: 19,965 (Change since 1990: +6.0%)
- Located along I-55 and US 61/67 at the south bank of Meramec River
- Latitude & Longitude: 38°25'58" N, 90°22'39" W
- Name origin: George Arnold
- Includes: Beck, Flamm City, Maxville, and Ten Brook
- Avoca (Historical)
- Located southeast of De Soto, near Valles Mines
- Latitude & Longitude: 38°03'25" N, 90°29'59" W
- Survey: T. 39 N., R. 5 E., Sec. 32
- Elevation: 720
- Civil township: Valle
- School district: Desoto 73
- USGS Quad: Halifax (Not shown)
- Maps: 1857 Colton, 1861, 1872, and 1886
- Bailey (Historical)
- Located somewhere west of Festus
- Latitude & Longitude: 38°13'30" N, 90°25'53" W
- Survey: T. 40 N., R. 5 E., Sec. 2
- Elevation: 430
- Civil township: River View
- School district: Festus R-6
- USGS Quad: Festus (Not shown)
- Barnhart (Unincorporated)
- Population: 6,108 (Change since 1990: +24.4%)
- Located near I-55 Exit 185 with Route M, between
Kimmswick and Pevely
- Latitude & Longitude: 38°20'39" N, 90°23'36" W
- Civil township: Imperial
- School district: Windsor C-1
- USGS Quad: Herculaneum
- Post office: Jan. 6, 1905 - Now
- Belew Creek (Unincorporated)
- Alternate name: Belews Creek
- Located at intersection Hillsboro House Springs Road and Glade Chapel Road north of Hillsboro
- Latitude & Longitude: 38°17'57" N, 90°33'60" W
- Survey: T. 41 N., R. 4 E., Sec. 10
- Elevation: 708
- Civil township: Central
- School district: Hillsboro R-3
- USGS Quad: Belew Creek
- Named for Belew Creek, which in turn was named
for William Belew, who settled in this area in 1778
- Source: Goodspeed (p. 371)
- Bushburg (Unincorporated)
- Alternate name: Bushberg
- Located on the Mississippi River between Sulphur Springs and Herculaneum
- Latitude & Longitude: 38°18'19" N, 90°22'35" W
- Civil township: Joachim
- School district: Dunklin R-5
- USGS Quad: Herculaneum
- Post office: Feb. 28, 1868 - Jun. 30, 1904 (Bushberg)
- Byers (Unincorporated)
- Located along US 61/US 67 between Arnold and Imperial
- Latitude & Longitude: 38°23'44" N, 90°22'27" W
- Civil township: Windsor
- School district: Windsor C-1
- USGS Quad: Oakville
- Maps: 1920 Clason and MoDOT
- Byrnes Mill (Fourth-class city)
- Population: 2,376 (Change since 1990: +50.6%)
- Located along MO 30 southeast of Eureka
- Latitude & Longitude: 38°26'16" N, 90°34'54" W
- Byrnesville (Unincorporated)
- Located on a county off MO 30 west of Scotsdale
- Latitude & Longitude: 38°23'34" N, 90°38'23" W
- Survey: T. 42 N., R. 3 E., Sec. 12
- Elevation: 462
- Civil township: Meramec
- School district: Northwest R-1
- USGS Quad: Pacific
- Named for the Byrne family; Patrick P. Byrne purchased a mill
in 1867 and operated it until his death in 1872, when
his son M. F. Byrne took over and then established a store and post office.
- Sources: Goodspeed (See biographical sketch of M. F. Byrne and Jefferson County)
- Cedar Hill (Unincorporated)
- Population: 1,703 (Change since 1990: -13.4%)
- Located near the intersection of MO 30 and Route BB
- Latitude & Longitude: 38°21'12" N, 90°38'28" W
- Survey: T. 42 N., R. 3 E., Sec. 25
- Civil township: Meramec
- School district: Northwest R-1
- USGS Quad: Cedar Hill
- Post office: May 18, 1933 - Now
- Cedar Hill Lakes (Village)
- Population: 229 (Change since 1990: +0.9%)
- Located just off MO 30 south of Cedar Hill and east of Dittmer
- Latitude & Longitude: 38°19'47" N, 90°39'27" W
- Coles Landing (Historical)
- Located on the east bank of Big River south of Blackwell right on the St. Francois County line at the end of Dickmann Road
- Latitude & Longitude: 38°00'26" N, 90°37'22" W
- Elevation: 590
- USGS Quad: Vineland
- Cottage Farm (Unincorporated)
- Located along Big River north of Ware just off Route C
- Latitude & Longitude: 38°14'22" N, 90°40'07" W
- Civil township: Big River
- School district: Grandview R-2
- USGS Quad: Fletcher
- Crystal City (Third-class city)
- Population: 4,247 (Change since 1990: +3.9%)
- Latitude & Longitude: 38°13'16" N, 90°22'44" W
- Post office: Oct. 10, 1872 - Now
- Danby (Unincorporated)
- Located near the Danby Road overpass over I-55, north of Route TT
- Latitude & Longitude: 38°06'33" N, 90°18'27" W
- Survey: T. 39 N., R. 6 E., Sec. 12
- Civil township: Plattin
- USGS Quad: Danby
- De Soto (City)
- Population: 6,375 (Change since 1990: +6.4%)
- Located along MO 21 south of Hillsboro
- Latitude & Longitude: 38°08'22" N, 90°33'18" W
- Name origin: Hernando De Soto
- Post office: Oct. 20, 1857 - Now
- Dittmer (Unincorporated)
- Previously known as: Dittmer's Store
- Located on MO 30 southwest of Cedar Hill
- Latitude & Longitude: 38°20'08" N, 90°41'17" W
- Survey: T. 42 N., R. 3 E., Sec. 34
- Elevation: 720
- Civil township: Meramec
- School district: Northwest R-1
- USGS Quad: Cedar Hill
- Post office: Jan. 20, 1870 - 1899 (Dittmer's Store), 1899 - Now (Dittmer)
- Engle (Historical)
- Located along Frisco railroad south of Barnhart
- Latitude & Longitude: 38°19'17" N, 90°23'57" W
- Survey: T. 41 N., R. 6 E., Sec. 6
- Civil township: Joachim
- School district: Dunklin R-5
- USGS Quad: Herculaneum
- Map: 1920 Clason
- Festus (Third-class city)
- Population: 9,660 (Change since 1990: +19.2%)
- Latitude & Longitude: 38°13'14" N, 90°23'45" W
- Post office: Aug. 21, 1883 - Now
- Fletcher (Unincorporated)
- Located on Route H near the Washington County line
- Latitude & Longitude: 38°09'57" N, 90°43'60" W
- Survey: T. 40 N., R. 3 E., Sec. 30
- Elevation: 572
- Civil township: Big River
- School district: Grandview R-2
- USGS Quad: Fletcher
- Flucom (Unincorporated)
- Located on Flucom Road between US 67 and Route T at
the bridge over Flucom Creek, northeast of Oakvale
- Latitude & Longitude: 38°06'04" N, 90°26'33" W
- Survey: T. 39 N., R. 5 E., Sec. 11, 14
- Civil township: Plattin
- School district: Desoto 73
- USGS Quad: Halifax
- Station on the Mississippi River and Bonne Terre line
- Frumet (Unincorporated)
- Located on Route H east of Fletcher
- Latitude & Longitude: 38°09'34" N, 90°41'35" W
- Survey: T. 40 N., R. 3 E., Sec. 33
- Elevation: 587
- Civil township: Big River
- School district: Grandview R-2
- USGS Quad: Fletcher
- Glen Park (Unincorporated)
- Located on a county road east of US 61/US 67 north of Herculaneum
- Survey: T. 41 N., R. 6 E., Sec. 5
- USGS Quad: Herculaneum
- Map: MoDOT
- Goldman (Unincorporated)
- Located just off MO 21 on Lemay Ferry Road
- Latitude & Longitude: 38°17'50" N, 90°31'17" W
- Elevation: 481
- Civil township: Central
- School district: Hillsboro R-3
- USGS Quad: Belew Creek
- Grubville (Unincorporated)
- Located at the junction of Route WW and Route Y near the Franklin County line
- Latitude & Longitude: 38°17'18" N, 90°45'17" W
- Survey: T. 41 N., R. 2 E., Sec. 13
- Elevation: 901
- Civil township: Big River
- School district: Northwest R-1
- USGS Quad: Lonedell
- Hematite (Unincorporated)
- Located on Route P between De Soto and Festus
- Latitude & Longitude: 38°12'07" N, 90°28'51" W
- Elevation: 440
- Civil township: Joachim
- School district: Festus R-6
- USGS Quad: Festus
- Hematite is an ore of iron that is blood red in powdered form.
The name is derived from the Greek word for blood.
- Founded: 1861 by Stephen Osborn
- Sources: Moser and Goodspeed (p. 445)
- Herculaneum (Fourth-class city)
- Population: 2,805 (Change since 1990: +24.0%)
- Located along US 61/US 67 just southeast of Pevely
- Latitude & Longitude: 38°16'06" N, 90°22'48" W
- High Ridge (Unincorporated)
- Population: 4,236 (Change since 1990: -4.2%)
- Located near intersection MO 30 and Route PP
- Latitude & Longitude: 38°27'32" N, 90°32'11" W
- Survey: T. 43 N., R. 3 E., Sec. 23
- Elevation: 927
- Civil township: High Ridge
- School district: Northwest R-1
- USGS Quad: House Springs
- Hillsboro (Fourth-class city)
- Population: 1,675 (Change since 1990: +3.1%)
- Located on MO 21 west of Festus and north of De Soto
- Latitude & Longitude: 38°13'56" N, 90°33'46" W
- Hoene Spring (Unincorporated)
- Located on Route W west of Byrnes Mill
- Latitude & Longitude: 38°27'05" N, 90°36'52" W
- Survey: T. 43 N., R. 4 E., Sec. 19
- Civil township: Meramec
- School district: Northwest R-1
- USGS Quad: House Springs
- Named for the Hoene family; William Hoene settled here in
1896 and later his son Harry developed a resort and eventually a subdivision.
- Map: MoDOT
- Horine (Unincorporated)
- Population: 923 (Change since 1990: -11.5%)
- Located just west of Herculeneum
- Latitude & Longitude: 38°15'60" N, 90°25'28" W
- Survey: Land Grant #924
- Elevation: 420
- Civil township: Joachim
- School district: Dunklin R-5
- USGS Quad: Herculaneum
- House Springs (Unincorporated)
- Located along Route MM near the intersection with MO 30 in
the vicinity of Byrnes Mill
- Latitude & Longitude: 38°24'32" N, 90°34'12" W
- Survey: T. 42 N., R. 4 E., Sec. 4
- Elevation: 474
- Civil township: High Ridge
- School district: Northwest R-1
- USGS Quad: House Springs
- Named for Adam House, who settled here ca. 1796 but
was killed by Indians in 1800
- Howe (Historical)
- Located south of Festus
- Point on the Mississippi River and Bonne Terre Line
- Map: 1920 Clason
- Imperial (Unincorporated)
- Previously known as: West Kimmswick
- Population: 4,373 (Change since 1990: +5.2%)
- Located just west of Kimmswick at I-55 Exit 186
- Latitude & Longitude: 38°22'11" N, 90°22'42" W
- Elevation: 446
- Civil township: Windsor
- School district: Windsor C-1
- USGS Quad: Herculaneum
- Jarvis (Unincorporated)
- Located on a county road between Goldman and Mapaville
- Latitude & Longitude: 38°16'05" N, 90°29'39" W
- Survey: T. 41 N., R. 5 E., Sec. 20
- Civil township: Joachim
- School district: Hillsboro R-3
- USGS Quad: Herculaneum
- Map: MoDOT
- Kimmswick (Fourth-class city)
- Population: 94 (Change since 1990: -30.4%)
- Latitude & Longitude: 38°21'55" N, 90°21'46" W
- Name origin: Theodore Kimm
- Founded: Oct. 1859 by Theodore Kimm
- Post office: Apr. 22, 1858-Present
- Knorpp (Unincorporated)
- Located next to Oakvale
- Latitude & Longitude: 38°05'18" N, 90°27'46" W
- Survey: T. 39 N., R. 5 E., Sec. 15
- Civil township: Plattin
- School district: Desoto 73
- USGS Quad: Halifax
- Map: 1904 McNally (Knorpp Sta. or Oakvale P.O.)
- Kohler City (Unincorporated)
- Liguori (Unincorporated)
- Local (Unincorporated)
- Located on Cedar Hill Road (Old MO 30) northeast of Cedar Hill near bridge
over Sand Creek
- Latitude & Longitude: 38°22'25" N, 90°37'22" W
- Survey: T. 42 N., R. 4 E., Sec. 18
- Elevation: 482
- Civil township: Meramec
- School district: Northwest R-1
- USGS Quad: Belew Creek
- Ludwig (Unincorporated)
- Located across Joachim Creek from Silica northwest of Crystal City
- Latitude & Longitude: 38°14'06" N, 90°25'08" W
- Civil township: River View
- School district: Festus R-6
- USGS Quad: Festus
- Mapaville (Unincorporated)
- Located at the intersection Route A and Route Z east of Hillsboro
- Latitude & Longitude: 38°14'56" N, 90°28'60" W
- Elevation: 677
- Civil township: Joachim
- School district: Hillsboro R-3
- USGS Quad: Festus
- McCormic (Unincorporated)
- Melzo (Unincorporated)
- Located on Route E near the St. Francois County line
- Latitude & Longitude: 38°00'36" N, 90°34'10" W
- Civil township: Valle
- USGS Quad: Vineland
- Morse Mill (Unincorporated)
- Located near intersection Route B and Route EE northwest of Hillsboro
- Latitude & Longitude: 38°16'36" N, 90°39'11" W
- Elevation: 495
- Civil township: Big River
- School district: Grandview R-2
- USGS Quad: Cedar Hill
- Named for John H. Morse, who settled here in 1847
- Mount Freedom (Unincorporated)
- Located on Route Y southeast of Ware
- Latitude & Longitude: 38°11'36" N, 90°38'50" W
- Survey: T. 40 N., R. 3 E., Sec. 13
- Elevation: 747
- Civil township: Big River
- School district: Grandview R-2
- USGS Quad: Fletcher
- Munsons (Unincorporated)
- Located just northwest of Festus
- Latitude & Longitude: 38°15'05" N, 90°25'34" W
- Civil township: River View
- School district: Festus R-6
- USGS Quad: Herculaneum
- Map: MoDOT
- Murphy (Unincorporated)
- Population: 9,048 (Change since 1990: -3.1%)
- Located just off MO 30 near the St. Louis County line
- Latitude & Longitude: 38°29'25" N, 90°29'13" W
- Civil township: Rock
- School district: Northwest R-1
- USGS Quad: Maxville
- Oakvale (Unincorporated)
- Located on Oakvale Road between US 67 and Route T, right
next to Knorpp
- Latitude & Longitude: 38°05'30" N, 90°27'36" W
- Survey: T. 39 N., R. 5 E., Sec. 15
- Civil township: Plattin
- School district: Desoto 73
- USGS Quad: Halifax
- Station on the Mississippi River and Bonne Terre Line between
Papin and Flucom
- Maps: 1904 McNally (Knorpp Sta. or Oakvale P.O.) and 1920 Clason
- Oermann (Unincorporated)
- Located just off MO 30 between Grubville and Dittmer
- Latitude & Longitude: 38°18'29" N, 90°43'24" W
- Survey: T. 41 N., R. 3 E., Sec. 7-8
- Elevation: 790
- Civil township: Big River
- School district: Northwest R-1
- USGS Quad: Cedar Hill
- Named for Charles Oermann, postmaster
- Olympian Village (Fourth-class city)
- Population: 669 (Change since 1990: -11.0%)
- Located near the interchange of US 67 and MO 110 east of De Soto
- Latitude & Longitude: 38°08'10" N, 90°27'28" W
- Name origin: Greek culture
- Otto (Unincorporated)
- Located near the intersection of Old MO 21 and Route M west of Antonia
- Latitude & Longitude: 38°22'15" N, 90°30'01" W
- Survey: T. 42 N., R. 5 E., Sec. 18
- Elevation: 879
- Civil township: Imperial
- School district: Fox C-6
- USGS Quad: Belew Creek
- Papin (Unincorporated)
- Located on Route JJ (Old US 67) near intersection with Route T
- Latitude & Longitude: 38°04'04" N, 90°28'14" W
- Survey: T. 39 N., R. 5 E., Sec. 27-28
- Civil township: Plattin
- School district: Desoto 73
- USGS Quad: Halifax
- Parkdale (Village)
- Population: 205 (Change since 1990: -3.3%)
- Latitude & Longitude: 38°28'41" N, 90°31'21" W
- Pevely (Fourth-class city)
- Population: 3,768 (Change since 1990: +33.1%)
- Located just north of Herculaneum
- Latitude & Longitude: 38°16'60" N, 90°23'42" W
- Founded: Sept. 1860 by Charles S. Rankin
- Plattin (Unincorporated)
- Located east of Olympian Village
- Latitude & Longitude: 38°07'52" N, 90°24'41" W
- Civil township: Plattin
- School district: Desoto 73
- USGS Quad: Festus
- Map: MoDOT
- Regina (Unincorporated)
- Located on Regina Road, just off Route BB, southeast
of Cedar Hill
- Latitude & Longitude: 38°19'35" N, 90°35'31" W
- Survey: T. 42 N., R. 4 E., Sec 32
- Civil township: Meramec
- School district: Hillsboro R-3
- USGS Quad: Belew Creek
- Riverside (Historical)
- Located near the Mississippi River just north of Herculaneum
- Latitude & Longitude: 38°17'12" N, 90°22'48" W
- Elevation: 439
- Civil township: Joachim
- USGS Quad: Herculaneum
- Rush Tower (Unincorporated)
- Located at end of Route AA near the Mississippi River
- Latitude & Longitude: 38°08'53" N, 90°17'31" W
- Elevation: 397
- Civil township: Plattin
- USGS Quad: Selma
- Schmitt (Historical)
- Located on Frisco railroad northwest of Pevely
- Latitude & Longitude: 38°17'60" N, 90°24'05" W
- Survey: T. 41 N., R. 6 E., Sec. 7
- Civil township: Joachim
- School district: Dunklin R-5
- USGS Quad: Herculaneum
- Map: 1920 Clason
- Scotsdale (Village)
- Population: 211 (Change since 1990: +9.3%)
- Located along MO 30 south of Byrnes Mill
- Latitude & Longitude: 38°23'56" N, 90°35'14" W
- Seckman (Unincorporated)
- Located on Lemay Ferry Road southwest of Arnold
- Latitude & Longitude: 38°24'08" N, 90°25'60" W
- Survey: T. 42 N., R. 5 E., Sec. 2
- Civil township: Imperial
- School district: Fox C-6
- USGS Quad: Maxville
- Selma (Unincorporated)
- Located just off US 61 southeast of the interchange with I-55
- Latitude & Longitude: 38°08'59" N, 90°20'29" W
- Survey: T. 40 N., R. 6 E., Sec. 34
- Civil township: Plattin
- USGS Quad: Selma
- Selma Station (Unincorporated)
- Located along the Mississippi River northwest of Rush Tower and northeast of Selma
- Survey: T. 40 N., R. 6 E., Sec. 23
- Elevation: 409
- Civil township: Plattin
- USGS Quad: Selma (Labeled "Selma (Sta.)")
- Station on the St. Louis and Memphis Line
- Silica (Unincorporated)
- Located just west of Festus along Old Route A
- Latitude & Longitude: 38°14'05" N, 90°25'33" W
- Elevation: 425
- Civil township: Joachim
- School district: Festus R-6
- USGS Quad: Festus
- Spring Forest (Unincorporated)
- Located just northeast of Seckman
- Latitude & Longitude: 38°24'19" N, 90°25'01" W
- Civil township: Imperial
- School district: Fox C-6
- USGS Quad: Maxville
- Sulphur Springs (Unincorporated)
- Located on the Mississippi River east of Barnhart
- Latitude & Longitude: 38°20'10" N, 90°22'26" W
- Civil township: Windsor
- School district: Windsor C-1
- USGS Quad: Valmeyer
- Sunnyside (Unincorporated)
- Located just north of Sulphur Springs
- Latitude & Longitude: 38°20'54" N, 90°22'10" W
- Survey: T. 42 N., R. 6 E., Sec. 29
- Elevation: 419
- Civil township: Windsor
- School district: Windsor C-1
- USGS Quad: Valmeyer
- Vada (Historical)
- Valles Mines (Unincorporated)
- Located near intersection US 67 and Route V near St. Francois County line
- Latitude & Longitude: 38°02'31" N, 90°29'59" W
- Survey: T. 39 N., R. 5 E., Sec. 32
- Elevation: 746
- Civil township: Valle
- USGS Quad: Halifax
- Station on the Mississippi River and Bonne Terre Line
- Maps: 1880 (in St. Francois Co.), 1886 (Valle's Mills), and 1897 Galbraith
- Victoria (Unincorporated)
- Previously known as: Victoria Station
- Located on Route P northeast of De Soto
- Latitude & Longitude: 38°10'40" N, 90°31'33" W
- Survey: T. 40 N., R. 4 E., Sec. 24
- Elevation: 469
- Civil township: Central
- School district: Hillsboro R-3
- USGS Quad: De Soto
- Founded: May 1859 by Henry B. Belt
- Source: Goodspeed (p. 445)
- Vineland (Unincorporated)
- Located just off MO 21 southwest of De Soto
- Latitude & Longitude: 38°05'43" N, 90°36'46" W
- Survey: T. 39 N., R. 4 E., Sec. 20
- Elevation: 695
- Civil township: Valle
- School district: Desoto 73
- USGS Quad: Vineland
- Ware (Unincorporated)
- Located at intersection of Route Y and Route C west of Hillsboro
- Latitude & Longitude: 38°12'49" N, 90°39'45" W
- Survey: T. 40 N., R. 3 E., Sec. 2
- Elevation: 552
- Civil township: Big River
- School district: Grandview R-2
- USGS Quad: Fletcher
- Weber Hill (Unincorporated)
- Located on Old MO 30 just southeast of Byrnes Mill
- Latitude & Longitude: 38°26'01" N, 90°33'09" W
- Survey: T. 43 N., R. 4 E., Sec. 27
- Civil township: High Ridge
- School district: Northwest R-1
- USGS Quad: House Springs
- Windsor Harbor (Historical)
- Located just south of Kimmswick
- Latitude & Longitude: 38°21'40" N, 90°21'40" W
- Civil township: Windsor
- Founded: Sept. 1859 by Freeman D. Water
Name origin
Named for President Thomas Jefferson
| Year | Population | Percent change |
|---|
| 1820 | 1,838 | -- |
| 1830 | 2,592 | +41.0% |
| 1840 | 4,296 | +65.7% |
| 1850 | 6,928 | +61.3% |
| 1860 | 10,344 | +49.3% |
| 1870 | 15,380 | +48.7% |
| 1880 | 18,736 | +21.8% |
| 1890 | 22,484 | +20.0% |
| 1900 | 25,712 | +14.4% |
| 1910 | 27,878 | +8.4% |
| 1920 | 26,555 | -4.7% |
| 1930 | 27,563 | +3.8% |
| 1940 | 32,023 | +16.2% |
| 1950 | 38,007 | +18.7% |
| 1960 | 66,377 | +74.6% |
| 1970 | 105,248 | +58.6% |
| 1980 | 146,183 | +38.9% |
| 1990 | 171,380 | +17.2% |
| 2000 | 198,099 | +15.6% |