- Location: Dunklin County, Missouri
- Legal status: Fourth-class city
- Population: 696 (Change since 1990: +31.1%)
- Name origin: Lewis Holcomb
- Located at the intersection of MO 25 and MO 53
- Latitude: 36°24'10" N (+36.4027)
- Longitude: 90°01'23" W (-90.0229)
- Public Land Survey: T. 21 N., R. 10 E., Sec. 31
- Civil township: Holcomb
- Land area: 0.61 square miles (390.7 acres)
As the crow flies, Holcomb is...
Name origin
Named for Lewis Holcomb, county sheriff
| Year | Population | Percent change |
|---|
| 1900 | 189 | -- |
| 1910 | 279 | +47.6% |
| 1920 | 358 | +28.3% |
| 1930 | 347 | -3.1% |
| 1940 | 388 | +11.8% |
| 1950 | 505 | +30.2% |
| 1960 | 436 | -13.7% |
| 1970 | 593 | +36.0% |
| 1980 | 632 | +6.6% |
| 1990 | 531 | -16.0% |
| 2000 | 696 | +31.1% |